The adipocyte enhancer binding protein 1 is antranscriptional repressor with carboxypeptidase (CP) activity. Thisnprotein binds to a regulatory sequence, adipocyte enhancer 1n(AE-1), located in the proximal promoter region of the adipose P2n(aP2) gene, which encodes the adipocyte fatty-acid binding protein.nIt is characterized as a member of the regulatory B-like CP family.nThis protein seems to be activated by a novel mechanism, wherebynthe direct binding of DNA enhances its protease activity.nAdipocyte-enhancer binding protein 1 may play a role inndifferentiated vascular smooth muscle cells.
应用类型
WB
免疫原
This AEBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-364 amino acids from the Central region of human AEBP1.
