RSPO4 is a member of the R-spondin family ofnproteins that share a common domain organization consisting of ansignal peptide, cysteine-rich/furin-like domain, thrombospondinndomain and a C-terminal basic region. The encoded protein may beninvolved in activation of Wnt/beta-catenin signaling pathways.nMutations in this gene are associated with anonychia congenital.nAlternate splicing results in multiple transcript variants.
应用类型
WB,IHC,FCM
免疫原
This RSPO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the C-terminal region of human RSPO4.
