ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
应用类型
WB,IHC
免疫原
This ZRANB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-692 amino acids from the C-terminal region of human ZRANB1.
