Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
应用类型
WB
免疫原
This TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-392 amino acids from the Central region of human TBCE.
