HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.
应用类型
WB
免疫原
This HAMP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the Central region of human HAMP.
