TASP1 is an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor.
应用类型
WB,IHC
免疫原
This TASP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-395 amino acids from the C-terminal region of human TASP1.
