The far upstream element-binding proteins FUBP, FUBP2, and FUBP3 comprise a family of single-strand DNA-binding proteins that possess all of the general features of more conventional transcription factors. The FUBPs each bind to a single sequence-specific strand of the far upstream element (FUSE; originally identified upstream of c-myc), and each possesses potent activation domains when fused to the GAL4 DNA-binding domain and assayed by transient transfection. These proteins have also been reported to bind RNA and participate in various steps of RNA processing, transport or catabolism.
应用类型
WB
免疫原
This FUBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human FUBP3.
