The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
应用类型
WB,IHC
免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180
