The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.
应用类型
WB,IHC,ICC
免疫原
The antiserum was produced against synthesized peptide derived from human ZAP-70. AA range:460-509
