Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.
应用类型
WB,IHC,ICC
免疫原
The antiserum was produced against synthesized peptide derived from human Catenin-beta around the phosphorylation site of Ser37. AA range:3-52