H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
应用类型
WB,IHC,ICC
免疫原
The antiserum was produced against synthesized peptide derived from human Histone H3 around the acetylated site of Lys9. AA range:3-52