- 中文名称
OTUD7B 一抗
- 英文名字
- OTUD7B Primary antibody
- 供应商
- Promab
- 产品货号
- PMB-P13072
- 产品报价
- ¥询价/100ul

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- OTUD7B (OTU domain-containing protein 7B), also known as ZA20D1 or Cezanne, is an 843 amino acid protein that localizes to both the nucleus and the cytoplasm. Expressed in a variety of tissues, including liver, kidney, heart and immature B-cells, OTUD7B functions to hydrolyze branched and linear forms of polyubiquitin, specifically deubiquinating Lys-48- and Lys-63-linked polyubiquitin chains. Via its ability to deubiquinate target proteins, OTUD7B regulates the inflammatory response within the cell and may play a role in cell survival. More specifically, OTUD7B forms a negative feedback loop in pro-inflammatory signaling, thereby suppressing NF˚B activity and helping to resolve inflammatory responses. OTUD7B contains one C-terminal A20-type zinc finger, one OTU domain and one N-terminal TRAF-binding domain through which it conveys its deubiquitinating activity.
- 应用类型
- IHC
- 免疫原
- Synthetic peptide of human OTUD7B
- 来源宿主
- Rabbit
- 反应性
- Human, Mouse
- 保存建议
- 4℃短期保存;-20℃长期保存。避免冻融循环。
- 其他
- ProMab 生物技术公司通过整合生物信息学、分子生物学、蛋白质表达、纯化技术、基因克隆、微生物学和免疫学,利用新型高通量技术开发重组蛋白、抗体和工程细胞系并将其商业化。专注于免疫治疗领域,特别是 CAR-T/NK 细胞技术。ProMab 还开发了一种新型的 mRNA 脂质纳米颗粒(mRNA-LNP)平台,用于即用型试剂和定制研究服务,以推进现有产品并扩展到更多的研究领域。

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