Syntaxin 19, also known as STX19, is a 294 amino acid peripheral membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the syntaxin family, suggesting a role in synaptic vesicle fusion. The gene encoding Syntaxin 19 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.