TRIM47 (tripartite motif-containing 47), also known as GOA (Gene overexpressed in astrocytoma protein) or RNF100 (RING finger protein 100), is a 638 amino acid protein that localizes to both cytoplasm and nucleus and belongs to the TRIM/RBCC family. While TRIM47 expression is low in most tissues, it is highly expressed in kidney tubular cells and overexpressed in astrocytoma tumor cells.
