- 中文名称
Semaglutide 生物类似药
- 英文名字
- Semaglutide Biosimilar
- 供应商
- Promab
- 产品货号
- PMB-B00057
- 产品报价
- ￥询价/20mg/60mg/180mg
- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻
- 背景资料
- What is research grade semaglutide biosimilar? Research grade semaglutide biosimilar has the same amino acid sequence as semaglutide, a recombinant peptide which presents 94% sequence homology to the human glucagon-like peptide-1 (GLP-1), differing primarily by two amino-acid substitutions at positions 8 and 34, where alanine and lysine are replaced by 2-aminoisobutyric acid and arginine, respectively. Liraglutide is made by attaching a C-18 fatty acid (stearic diacid) with a glutamic acid spacer on the remaining lysine residue at position 26 of the peptide precursor. Semaglutide is resistant to the dipeptidylpeptidase-4 enzyme whic degrades the natural hormone. As a GLP-1 receptor agonist, Semaglutide mimics the action of the human incretin glucagon-like peptide-1 (GLP-1), thereby increasing insulin secretion and increasing blood sugar disposal and improving glycemic control. Semaglutide is an anti-diabetic medication used to treat type 2 diabetes, obesity, and chronic weight management.
- 应用类型
- Flow cytometry, animal model study
- 免疫原
- 来源宿主
- CHO cells
- 反应性
- Human
- 保存建议
- Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
- 其他
- Acylated Glucagon-like Peptide-1 Receptor Agonist, Human GLP-1 Receptor Agonist, Human GLP-1 Analog
- 注意
-
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