- 中文名称
Muromonab 生物类似药, CD3 单克隆抗体
- 英文名字
- Muromonab Biosimilar, CD3 Monoclonal Antibody
- 供应商
- Promab
- 产品货号
- PMB-B00047
- 产品报价
- ￥询价/1mg/5mg/20mg
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- Muromonab Biosimilar uses the same protein sequences as the therapeutic antibody muromonab (OKT3).nnMuromonab (OKT-3) is a monoclonal anti-CD3 antibody used as immunosuppressive therapy in kidney, heart, and liver transplant patients.nnMurine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a).nnMuromonab binds to the T-cell surface glycoprotein CD3 epsilon chain. It appears to kill CD-3 positive cells by inducing Fc mediated apoptosis, antibody mediated cytotoxicity and complement-dependent cytotoxicity.
- 应用类型
- Flow cytometry, animal model study
- 免疫原
- Human CD3
- 来源宿主
- CHO cells
- 反应性
- Human
- 保存建议
- Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
- 其他
- cluster of differentiation 3, CD3D, CD3E, CD3G, OKT-3, OKT3
- 注意
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