- 中文名称
Tocilizumab 生物类似药, 人 IL-6R 单克隆抗体
- 英文名字
- Tocilizumab Biosimilar, Human IL-6R Monoclonal Antibody
- 供应商
- Promab
- 产品货号
- PMB-B00026
- 产品报价
- ¥询价/1mg/5mg/20mg

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- What is tocilizumab biosimilar research grade? Tocilizumab biosimilar uses the same protein sequences as the therapeutic antibody tocilizumab. Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. Interleukin 6 (IL-6) is a pro-inflammatory cytokine produced by cells including T-cells, B-cells, lymphocytes, monocytes, fibroblasts. IL-6 rapidly induces C-reactive protein, serum amyloid A, fibrinogen, haptoglobin, and α-1-antichymotrypsin while inhibiting production of fibronectin, albumin, and transferrin. IL-6 also induces antibody production, induces cytotoxic T-cell differentiation, and inhibits regulatory T-cell differentiation. Tocilizumab binds soluble and membrane bound IL-6 receptors, preventing IL-6 mediated inflammation.
- 应用类型
- Flow cytometry, animal model study
- 免疫原
- Human IL-6R
- 来源宿主
- CHO cells
- 反应性
- Human
- 保存建议
- Store at 4°C 1 month, store at -20°C to -70°C 12 month. protected from prolonged exposure to light. Avoid freeze/thaw cycles.
- 其他
- ProMab 生物技术公司通过整合生物信息学、分子生物学、蛋白质表达、纯化技术、基因克隆、微生物学和免疫学,利用新型高通量技术开发重组蛋白、抗体和工程细胞系并将其商业化。专注于免疫治疗领域,特别是 CAR-T/NK 细胞技术。ProMab 还开发了一种新型的 mRNA 脂质纳米颗粒(mRNA-LNP)平台,用于即用型试剂和定制研究服务,以推进现有产品并扩展到更多的研究领域。

- 注意
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