This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.
应用类型
WB,IHC,ICC,FCM
免疫原
Purified recombinant fragment of human NDC80 (AA: 443-642) expressed in mammalian cells.
