This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.
应用类型
ICC,FCM
免疫原
Purified recombinant fragment of human BNIP3 (AA: 50-155) expressed in E. Coli.