DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
应用类型
WB
免疫原
Purified recombinant fragment of human DNMT1 (AA: 1317-1616) expressed in E. Coli.