The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
应用类型
WB,FCM
免疫原
Purified recombinant fragment of human ATG16L1 (AA: 11-257) expressed in E. Coli.
