Phosphoinositide-dependent kinase 1 (PDPK1, PDK1) is a serine/threonine protein kinase integral to the function of the PI 3-K/Akt signaling pathway. PDK1 and mTORC2 both phosphorylate and activate PKB/Akt, ensuring a cellular response to stimuli such as growth factors and insulin signaling. Akt is the main effector of PDK1.
应用类型
WB,ICC,FCM
免疫原
Purified recombinant fragment of human PDPK1 (AA: 457-556 expressed in E. Coli.
