This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
应用类型
IHC,ICC,FCM
免疫原
Purified recombinant fragment of human SYCP3 (AA: 27-128) expressed in E. Coli.
