This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.
应用类型
IHC,ICC,FCM
免疫原
Purified recombinant fragment of human ZEB1 (AA: 967-1108) expressed in E. Coli.