The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
应用类型
IHC
免疫原
Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.