The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
应用类型
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免疫原
Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.
