The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.
应用类型
WB,IHC
免疫原
Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.
