PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.
应用类型
WB
免疫原
Purified recombinant fragment of human PRDM1 expressed in E. Coli.