Stratifin is part of the 14-3-3 family. The 14-3-3 family of proteins plays an important regulatory function in signal transduction， checkpoint control， apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are 7 isoforms， beta， gamma， epsilon， sigma， zeta， tau and eta that have been identified in mammals. Stratifin is an epithelial cell marker that functions as a tumor suppressor whose expression can be down regulated via methylation. Failure of Stratifin expression results in a defective G2/M phase checkpoint and results in epithelial and non-epithelial tumorigenesis.
序列
请咨询我们客服或者请查看品牌官方网站
来源宿主
大肠杆菌中重组表达
溶解建议
提供的人Tyr-3/Trp-5单氧酶激活蛋白Sigma（Stratifin）产品为过滤灭菌的无色溶液；其中人Tyr-3/Trp-5单氧酶激活蛋白Sigma（Stratifin）产品溶解于20mM Tris pH 8，50mM NaCl，10%甘油溶液中.
