YWHAB belongs to the 14-3-3 family of proteins which are in charge for signal transduction by binding to phosphoserine-containing proteins. YWHAB is found in both plants and mammals. YWHAB protein interacts with RAF1 and CDC25 phosphatases,thus linking mitogenic signaling and the cell cycle machinery. YWHAB is an adapter protein involved in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAB binds to a large number of proteins by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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来源宿主
大肠杆菌中重组表达
溶解建议
提供的人Tyr-3/Trp-5单氧酶激活蛋白Beta(YWHAB)产品为过滤灭菌的无色溶液;其中人Tyr-3/Trp-5单氧酶激活蛋白Beta(YWHAB)产品溶解于20mM Tris pH 8,1mM EDTA,50mM NaCl溶液中.