Adenylate kinases play a role in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. There are 3 types of adenylate kinase isozymes， AK1， AK2， and AK3 in vertebrates. Expression of these isozymes are tissue-specific and developmentally regulated. AK2 is localized in the mitochondrial intermembrane space and is involved in apoptosis. AK2 is mutated in individuals with reticular dysgenesis.
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来源宿主
大肠杆菌中重组表达
溶解建议
提供的腺苷激酶2（AK2）产品为过滤灭菌的无色溶液；其中腺苷激酶2（AK2）产品溶解于20mM Tris pH 7.5，5mM DTT，20%甘油溶液中.
