Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK3 encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. Hexokinase3 lacks the hydrophobic N-terminal sequence critical for targeting to mitochondria. Hexpkinase3 may have anabolic functions, providing H6P for glycogen or lipid synthesis.
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来源宿主
大肠杆菌中重组表达
溶解建议
提供的人己糖激酶-3(HK-3)产品为过滤灭菌的无色溶液;其中1mg/ml人己糖激酶-3(HK-3)产品溶解于20mM Tris pH 8.0,10%甘油溶液中.