PRKAB2 is a regulatory subunit of the AMP-activated protein kinase （AMPK）. AMPK is a heterotrimer contains an alpha catalytic subunit and non-catalytic beta and gamma subunits. AMPK is a significant energy-sensing enzyme that supervises cellular energy status. AMPK is activated as a reply to cellular metabolic stresses， therefore phosphorylates and inactivates acetyl-CoA carboxylase （ACC） and beta-hydroxy beta-methylglutaryl-CoA reductase （HMGCR）， vital enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 is a positive regulator of AMPK activity and highly expressed in skeletal muscle.
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来源宿主
大肠杆菌中重组表达.
溶解建议
提供的重组人腺苷单磷酸活化蛋白激酶B2（非催化亚基）产品形式为无菌的无色溶液.
保存建议
建议将重组人腺苷单磷酸活化蛋白激酶B2（非催化亚基）产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.长期保存，推荐添加载体蛋白 （0.1% HSA or BSA）.请避免反复冻融.
