Mitogen-activated protein kinase 9 （MAPK9） belongs to the MAP kinase family. MAP kinases function as an integration point for numerous biochemical signals， and are involved in a broad variety of cellular processes such as proliferation， differentiation， transcription regulation and development. MAPK9 targets specific transcription factors， and consequently mediates immediate-early gene expression in response to diverse cell stimuli. As an active dimer， MAPK9 can translocate to the nucleus and control transcription through its effects on c-Jun， ATF-2， and other transcription factors. MAPK9 blocks the ubiquitination of tumor suppressor p53， and so it increases the stability of p53 in nonstressed cells.
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大肠杆菌中重组表达.
溶解建议
提供的重组人促分裂原活化蛋白激酶9产品形式为无菌的无色溶液.
保存建议
建议将重组人促分裂原活化蛋白激酶9产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.长期保存，推荐添加载体蛋白 （0.1% HSA or BSA）.请避免反复冻融.
