CCNA2 is a member of the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins act as regulators of CDK kinases. Various cyclins demonstrate distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Contrary to cyclin A1, which is present only in germ cells, CCNA2 is expressed in all tissues tested. CCNA2 binds and activates CDC2 or CDK2 kinases, and consequently promotes both cell cycle G1/S and G2/M transitions.
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大肠杆菌中重组表达.
溶解建议
提供的重组人细胞周期素A2产品形式为无菌的无色澄清溶液.
保存建议
建议将重组人细胞周期素A2产品整瓶保存于4℃可保存2-4周. 长期保存,请置于-20℃.长期保存,推荐添加载体蛋白 (0.1% HSA or BSA).请避免反复冻融.