MAPK14 belongs to the MAP kinase family and is most associated with p38 MAP kinases（MAPKs）. MAPKs are activated mainly as a reaction to cellular stress and inflammatory cytokines， and inhibitors that target the MAPK14 and MAPK11 have demonstrated ability to cure inflammatory disease. The substrates of this kinase contain transcription regulator ATF2， MEF2C， and MAX， cell cycle regulator CDC25B， and tumor suppressor p53， which demonstrate the parts of MAPK14 in stress-related transcription， cell cycle regulation and genotoxic stress response.
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大肠杆菌中重组表达.
溶解建议
提供的重组人促分裂原活化蛋白激酶14产品形式为无菌的无色溶液.
保存建议
建议将重组人促分裂原活化蛋白激酶14产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.长期保存，推荐添加载体蛋白 （0.1% HSA or BSA）.请避免反复冻融.
