MAPK11 belongs to the MAP kinase family and is most associated with p38 MAP kinases （MAPKs）. MAPKs are activated mainly as a reaction to cellular stress and inflammatory cytokines， and inhibitors that target the MAPK14 and MAPK11 have demonstrated ability to cure inflammatory disease. MAPK11 cooperates with HDAC3 and Promyelocytic leukemia protein and takes part in a signal transduction pathway which is activated by alterations in the osmolarity of the extracellular environment， by environmental stress， or by cytokines.
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大肠杆菌中重组表达.
溶解建议
提供的重组人促分裂原活化蛋白激酶11产品形式为无菌的无色溶液.
保存建议
建议将重组人促分裂原活化蛋白激酶11产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.长期保存，推荐添加载体蛋白 （0.1% HSA or BSA）.请避免反复冻融.
