uV RESISTANCE LOCuS8 (uVR8) is a unique uV-B photoreceptor that following the aBsorption of uV-B photons, initiates changes in gene expression. uVR8 is located in the nucleus and the cytosol. Associates with chromatin via histones. uVR8 interaction with COP1 is negatively regulated By RuP1 and RuP2.