Triosephosphate isomerase (TPI) catalyzes the interconversion of glyceraldehyde-3-phosphate to dihydroxyacetone phosphate. Photosynthetic organisms generally contain two isoforms of TPI located in both cytoplasm and chloroplasts. The chloroplastic isoform participates in the Calvin-Benson cycle, a key photosynthetic process responsible for carbon fixation.