- 中文名称
Protein Kinase C, phosphorylated (PKC) BioAssay Sample Kit
- 英文名字
- Protein Kinase C, phosphorylated (PKC) BioAssay Sample Kit
- 供应商
- USBiological
- 产品货号
- P9103-22
- 产品报价
- ￥1/9x20ul
- 产品说明书
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- 银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- USBiological品牌是全球有名的抗原抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理，是行业中少有的致力于服务客户，帮助客户，且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应，专业的产品和解决方案支持，稳健快捷的交货周期，优质放心的售后服务。我们致力于为您提供有价值的产品和服务，在意您的成功！
- 产品描述
- Activation of PKC is one of the earliest events in the cascade leading to a variety of cellular responses such as secretion, gene expression, proliferation and muscle contraction (1,2). There are multiple PKC isoforms, including classical PKCs (a, b1, b2 and g), which bind calcium, diacylglycerol (DAG) and phospholipids; novel PKCs (d, e, n and theta), which are regulated by DAG and phospholipids; and atypical PKCs: zeta and lambda, which lack calcium-or DAGbinding domains. The activity of PKC is under control by three distinct phosphorylations. Specifically, threonine 500 at the activation loop, the threonine 641 autophosphorylation site and the serine 660 hydrophobic site at the carboxy terminus of PKCb2 are phosphorylated in vivo (2). For the atypical PKC isoforms, there is no phosphorylation in the hydrophobic region, which has a glutamic residue in place of the serine or threonine residue found in other PKC isoforms. The enzyme PDK1 or perhaps a close relative is responsible for PKC activation loop phosphorylation in a phosphoinositide 3 kinase (PI3K) dependent fashion (3). Protein Kinase D (PKD), also called PKCu, is a serine/ threonine kinase (4,5). Activation of PKD/PKCu is dependent on the phosphorylation of two activation loop sites, namely serine 744 and serine 748, via a PKCdependent signal transduction pathway (6). In addition to the two activation loop sites, the C-terminal serine 916 has been identified as an autophosphorylation site for PKD/PKCu. Phosphorylation of the serine 916 site is correlated with PKD/PKCu catalytic activity (7). Phospho-PKC Antibody Sampler Kit contains 40ul of each primary antibody and 100ul of antirabbit IgG secondary antibody (HRP conjugated).Kit components: Crossreactivity: Application: Molecular Weight:P9103-22A: Protein Kinase C, pan, phosphorylated (PKC) 1x20ulrabbit H M R Mk W IP 78-82, 85 P9103-22B: Protein Kinase C, alpha, beta 2, phosphorylated (Thr638/641) (PKCa,bII) 1x20ulrabbit H M (R) Mk W IP 80, 82 P9103-22C: Protein Kinase C, delta, phosphorylated (Thr505) (PKCd) 1x20ul rabbit H M R Hm Mk W IHC 78 P9103-22D: Protein Kinase C, delta, phosphorylated (Ser643) (PKCd) 1x20ulrabbit H M R Mk W IHC 78 P9103-22E: Protein Kinase C, mu, Protein Kinase D, phosphorylated (Ser744/748) (PKCm, PKD) 1x20ulrabbit H M R Mk W IHC 115 P9103-22F: Protein Kinase C, mu, Protein Kinase D, phosphorylated (Ser916) (PKCm, PKD) 1x20ul rabbit H M R Mk W IP 115 P9103-22G: Protein Kinase C, mu, Protein Kinase D (PKCm, PKD) 1x40ulrabbit H M R Mk W 115 P9103-22H: Protein Kinase C, theta, phosphorylated (Thr538) (PKCt) 1x20ulrabbit H (M) R Mk W IHC 79 P9103-22J: Protein Kinase C, zeta, lambda, phosphorylated (Thr410/403) (PKCz,l) 1x20ulrabbit H M R Mk W IHC 76 P9103-22K: IgG, H&L (HRP) GtxRb 1x100ulgoat Storage and Stability:For long-term storage, aliquot and store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- 产品特点
- 针对Protein Kinase C, phosphorylated (PKC) BioAssay Sample Kit该产品的特点优势，欢迎查阅官网提供的产品说明书。
- 保存建议
- 建议收到Protein Kinase C, phosphorylated (PKC) BioAssay Sample Kit产品后将其置于-20°C保存。
- 其他
- Usbiological公司是美国著名的抗体和生化试剂供应商，生产世界上种类最多的抗体，用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品，为科研用户提供了诸多超值选择。
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- 注意
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该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
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