Tumor Necrosis Factor-α (TNF-α) is a highly pleiotropic cytokine with multiple activities other than its originally discovered role of tumor necrosis in rodents. It contributes to both inflammations during infections and anti-inflammatory/tissue repair processes after clearance of infection. TNF-α is mainly produced by activated macrophages, T lymphocytes, and natural killer (NK) cells. The activity of TNF-α is mediated through two cell surface receptors, TNF-R1 (p55) and TNF-R2 (p75) that differ in their signaling activity. TNF-α's primary role is in the regulation of immune cells. It can induce cell death of certain tumor cell lines. About 28% of cancers are susceptible to direct cell killing mediated by soluble TNF-α.
序列
提供的Human CellExp™TNF-α细胞外结构域，人类重组Human CellExp™ TNF-alpha Extracellular Domain, Human Recombinant是Biovision品牌中国区域总代理艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™TNF-α细胞外结构域，人类重组Human CellExp™ TNF-alpha Extracellular Domain, Human Recombinant产品来源宿主，查看该产品说明书，或者在线咨询我们。
溶解建议
Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
