中文名称

Human CellExp™TIM-3 / HAVCR2，食蟹猴重组

英文名字

Human CellExp™ TIM-3 / HAVCR2, Cynomolgus Recombinant

供应商

Biovision

产品货号

P1391-10

产品报价

￥已停产

产品说明书

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购买方式

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产品新闻

背景资料

Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428, KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.

序列

提供的Human CellExp™TIM-3 / HAVCR2，食蟹猴重组Human CellExp™ TIM-3 / HAVCR2, Cynomolgus Recombinant是Biovision品牌中国区域总代理艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。

来源宿主

提供的Human CellExp™TIM-3 / HAVCR2，食蟹猴重组Human CellExp™ TIM-3 / HAVCR2, Cynomolgus Recombinant产品来源宿主，查看该产品说明书，或者在线咨询我们。

溶解建议

Centrifuge the vial prior to opening. Reconstitute in sterile deionized water. Do not vortex. It is recommended to store at -20°C.

保存建议

在您收到艾美捷发出的Human CellExp™TIM-3 / HAVCR2，食蟹猴重组产品后，建议将其置于-20ºC保存。

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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