Human CellExp™CSF1R / CD115，小鼠重组，Fc标签-Human CellExp™ CSF1R/CD115, mouse recombinant, Fc Tag代理/参数/厂家-重组蛋白-艾美捷科技有限公司

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背景资料: Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the typeⅢ subfamily of receptor tyrosine kinases (RTKs). CSF1R is a receptor for a cytokine called colony stimulating factor 1, The protein encoded by the CSFR1 gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most, if not all, of the biological effects of this cytokine. Ligand binding activates CSFR1 through a process of oligomerization and transphosphorylation . Mutations in CSF1R are associated with chronic myelomonocytic leukemia and type M4 acute myeloblastic leukemia. Increased levels of CSF1R1 are found in microglia in Alzheimer's disease and after brain injuries. The increased receptor expression causes microglia to become more active. Both CSF1R, and its ligand colony stimulating factor 1 play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis.

序列: 提供的Human CellExp™CSF1R / CD115，小鼠重组，Fc标签Human CellExp™ CSF1R/CD115, mouse recombinant, Fc Tag是Biovision品牌中国区域总代理艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。

来源宿主: 提供的Human CellExp™CSF1R / CD115，小鼠重组，Fc标签Human CellExp™ CSF1R/CD115, mouse recombinant, Fc Tag产品来源宿主，查看该产品说明书，或者在线咨询我们。

溶解建议: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

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