VSIG4 (V-set and immunoglobulin domain containing 4), as known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
序列
提供的Human CellExp™VSIG4，人类重组Human CellExp™ VSIG4, human recombinant是Biovision品牌中国区域总代理艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的Human CellExp™VSIG4，人类重组Human CellExp™ VSIG4, human recombinant产品来源宿主，查看该产品说明书，或者在线咨询我们。
溶解建议
Reconstitute in 1X PBS to the desired protein concentration.
