Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
序列
提供的人类CellExp KLF4-TAT，人类重组Human CellExp KLF4-TAT, Human Recombinant是Biovision品牌中国区域总代理艾美捷科技产品，具体的蛋白序列可查看提供的英文版本产品说明书。
来源宿主
提供的人类CellExp KLF4-TAT，人类重组Human CellExp KLF4-TAT, Human Recombinant产品来源宿主，查看该产品说明书，或者在线咨询我们。
溶解建议
Reconstitute in sterile deionized water to a concentration of 0.1-1.0 mg/ml. Do not vortex. Additional carrier protein (example 0.1% BSA) is recommended for long term storage.
