Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. CBY1 encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
应用类型
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免疫原
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来源宿主
该Rabbit IgG polyclonal antibody for Branched-chain-amino-acid aminotransferase, mitochondrial(BCAT2) detection. Tested with WB, IHC in Human.产品的来源宿主详情查看产品说明书。