AP1AR is necessary for adaptor protein complex 1 (AP-1) -dependent transport between the trans-Golgi network and endosomes. It regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes.
