- 中文名称
为建立检测小鼠血清和细胞培养上清液中IL-10的夹心ELISA试剂盒。
- 英文名字
- For the development of sandwich ELISA kit to measure mouse IL-10 in cell culture supernatants and serum.
- 供应商
- Nordic BioSite
- 产品货号
- NDC-KBB-FXPJWT-5
- 产品报价
- ¥询价/5plates

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Interleukin-10, also called cytokine synthesis inhibitory factor, is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production. IL-10 is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system. IL-10 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. IL-10 significantly affects chemokine biology, because human IL-10 inhibits chemokine production and is a specific chemotactic factor for CD8+ T cells. It suppresses the ability of CD4+ T cells, but not CD8+ T cells, to migrate in response to IL-8. Interleukin-10 gene polymorphisms and interleukin-10 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation.1 The interleukin-10 locus contributes to the heritability of psoriasis susceptibility. With regard to sudden infant death, IL-10 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease The mIL-10 gene is mapped to mouse chromosome 1 and the hIL-10 gene is also mapped to human chromosome 1. The standard product used in this kit is recombinant human IL-10, consisting of 160 amino acids with the molecular mass of 18.6KDa.
- 产品描述
- 白细胞介素-10,也称为细胞因子合成抑制因子,与肿瘤发生有关,并且已经显示其基因启动子多态性与不同的产生量相关。IL-10是一种重要的细胞因子,具有抗炎、抗免疫、抗纤维化等作用。它也是一种重要的调节性细胞因子,其参与延伸到人类免疫系统的不同区域。IL-10是最近描述的一种天然内源性免疫抑制细胞因子,已在人、鼠和其它生物体中鉴定。IL-10显著影响趋化因子生物学,因为人IL-10抑制趋化因子产生,并且是CD8 + T细胞的特异性趋化因子。它抑制CD4 + T细胞,但不抑制CD8 + T细胞响应IL-8迁移的能力。白细胞介素-10基因多态性和白细胞介素-10产生能力可能与肾移植后皮肤鳞状细胞癌的发生有关。1白细胞介素-10基因座与银屑病易感性的遗传性有关。关于婴儿猝死,IL-10是特别感兴趣的。这是一种免疫调节细胞因子,在感染性疾病的发展中起重要作用。mIL-10基因定位于小鼠1号染色体,hIL-10基因也定位于人1号染色体。本试剂盒使用的标准品为重组人IL-10,由160个氨基酸组成,分子量为18.6KDa。
- 产品特点
- ES(雌激素)ELISA试剂盒
- 保存建议
- -20°C
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典,成立于1997年,旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合,代理了遍布欧洲和美国的顶级生物试剂制造商,是欧洲知名的一站式生物试剂代理商。除了作为分销商之外,Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体,蛋白和试剂盒,产品适用范围涵盖15个不同的物种(人,牛,犬,鲶鱼,鸡,海豚,马,猫,豚鼠,小鼠,绵羊,兔子,大鼠,猪和火鸡),可为您提供一站式的生命科学研究解决方案~
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