- 中文名称
用于开发夹心ELISA试剂盒以测定细胞培养上清液、血清和血浆（肝素、EDTA）中的小鼠TFF1。
- 英文名字
- For the development of sandwich ELISA kit to measure mouse TFF1 in cell culture supernatants, serum and plasma (heparin, EDTA).
- 供应商
- Nordic BioSite
- 产品货号
- NDC-KBB-AFC98Z-5
- 产品报价
- ￥询价/5plates
- 产品说明书
- 点击查看
- 购买方式
- 90%产品中国有现货库存。银行转账、电汇、支票、现金，在线支付宝及网银支付，或直接与我们电话联系400-6800-868
- 产品新闻
- 背景资料
- TFF1(Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
- 产品描述
- TFF1（三叶因子1），也称为pS2，是一种在人类中由TFF1基因编码的蛋白质。三叶草家族成员的特征在于具有至少一个拷贝的三叶草基序，即含有三个保守二硫键的40个氨基酸的结构域。是在胃肠道粘膜表达的稳定分泌蛋白。其功能尚不明确，但可保护粘膜免受损伤、稳定粘液层并影响上皮愈合。结果表明，正常人尿中TFF1对草酸钙晶体生长有抑制作用。尿TFF1显示出与肾钙蛋白相似的抑制效力，并且抑制是剂量依赖性的，并且被TFF1抗血清抑制，特别是被针对TFF1C末端的抗血清抑制。特发性草酸钙肾结石患者尿液中TFF1的浓度和相对含量显著低于对照组。该基因在胃粘膜中表达，由于其在人肿瘤中的表达也已被研究。该基因和其他两个相关的三叶草家族成员基因被发现在21号染色体上的一个簇中。
- 产品特点
- 人可替宁ELISA试剂盒（竞争性EIA）
- 保存建议
- -20°C
- 其他
- Nordic BioSite(北欧生物) 总部位于瑞典，成立于1997年，旨在分销研究和诊断领域的高质量和创新产品。 Nordic BioSite 被公认为整个北欧生物医学研究和诊断产品领域的领导者。他们拥有超过570万种的产品组合，代理了遍布欧洲和美国的顶级生物试剂制造商，是欧洲知名的一站式生物试剂代理商。除了作为分销商之外，Nordic BioSite 还拥有不断增长的自产产品线——BioSite mAb、BioSite ELISA、BioSite Flow、Optibodies和 BioSite Protein, 目前艾美捷代理的是Nordic BioSite自产产品线(共26W+产品)。Nordic BioSite的产品类型主要是抗体，蛋白和试剂盒，产品适用范围涵盖15个不同的物种(人，牛，犬，鲶鱼，鸡，海豚，马，猫，豚鼠，小鼠，绵羊，兔子，大鼠，猪和火鸡)，可为您提供一站式的生命科学研究解决方案~
-
- 注意
-
该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。
-
