Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6.
应用类型
该Caspase 9 (phospho-Tyr153)产品的应用类型详情查看产品说明书。
免疫原
Synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyrosine 153.
来源宿主
rabbit
反应性
该Rabbit IgG polyclonal antibody for Caspase-8(CASP8) detection. Tested with WB, IHC in Human.产品的反应性详情查看产品说明书。
